Today, the crystal structure of Ceg10, an effector protein from Legionella was deposited and released at the RSCB Protein Data Bank (PDB). While a lot remains to be determined about its function and targets during an infection, we are excited to finally release some of what we have learned about this protein in the last 8 years! The Ceg10 crystal structures are part of a collaborative project between Dr. Heisler’s lab and the Gammon, Alto, and Taglialucci lab’s at UT Southwestern Medical School.

More about what Ceg10 does during a viral infection can be found in a recent preprint: Exploiting Bacterial Effector Proteins to Uncover Evolutionarily Conserved Antiviral Host Machinery
The crystal structures can be found at the RSCD PDB: 9B8D and 9B8E